Baccano!

In the late 1930 of California, Isaac and Miria are in a mine digging for gold and months pass without any success. They receive a letter from Ennis in New York, who ask for them to return but they don't have any money. So after stealing some cash from the mafia they board the Flying Pussyfoot to New York, where they happen to spot a lot of suspicious characters. Whilst Isaac and Miria are getting acquainted with Jacuzzi and Nice something to do with the "Lemurs" is about to begin.